ketone

for nucleophilic attack in ketone, with increasing + I effect on carbon of carbonyl group, the reactivity should increase or decrease ?

9 Answers

1357
Manish Shankar ·

The reactivity should decrease as it will reduce the positive charge on the carbon atom

1
big looser ......... ·

but + I effect will increase the + positive charge on carbon

1357
Manish Shankar ·

I think you are confudsed
+I are electron releasing which will decrease the +ve charge on carbon

1
big looser ......... ·

oh sorry
but reducing + ve charge will increase the stability of carbocation and its formation will become easier so, don't you think that it will increase the reactivity

1
°ღ•๓яυΠ·

hmmmmmmm...........

nucleophile is lewis base means itz eltron rich so it attckes carbon .....of d carbonyl compund coz it has positive chrge

wen d eltron donatin susbtituents increse d positive chrge on carbon whm d nucleophile will attck will decrese as positve chrage decrese d rxtivity decrese

corrct me if m wrng :'(

1357
Manish Shankar ·

integrations you are absolutely right

1
big looser ......... ·

i am still confused .. wats wrong in my statement

1
°ღ•๓яυΠ·

hey b y u need d stability of carbon
wat we need is d chrge on nucleophile and carbonyl carbon so bas
jab woh carbon par charge decraese hoga .nucleophile will nt b dat attrcted 2wrds it as it wud hav been if d charge wud hav had remein intact or say charge on crabon wud ahv has incerse(+ve)

1
big looser ......... ·

ok integration i agree with you

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